How Generic Avodart (Dutasteride) Works
Dutasteride is the sole active ingredient of the branded drug called Avodart used to treat benign prostatic hyperplasia (nonmalignant prostate enlargement). It is a dual 5-alpha-reductase blocker and, therefore, since it blocks both isoforms of this enzyme it possesses strong anti-androgenic effects. It works by inhibiting the conversion of testosterone into dihydrotestosterone (DHT). DHT was found to be the primary cause of the prostate gland enlargement. Avodart (dutasteride) helps shrink enlarged prostate and thus reduces urinary blockage and improves urine flow. Dutasteride was also subjected to clinical trials regarding its use in preventing prostate cancers but its originator finally decided not to seek an approval for this application. Despite that some doctors recommend Avodart off-label as a preventive treatment to patients who are at high risk of developing low-grade prostate cancers.
Since this drug is similar to Propecia's finasteride in terms of its chemical structure and effects, it became to be used to treat hair loss in male patients. Dutasteride has recently completed Phase III clinical trials for treating male pattern baldness and the final study results are pending. Nevertheless, some hair restoration doctors already prescribe it to their patients who, after years of continuous use of Propecia, no longer respond to it. Preliminary results of the recently conducted clinical study of dutasteride's effects on hair loss suggested that it is a more powerful DHT inhibitor than finasteride at half dose and has been proven to work better in the frontal area of the scalp in re-growing hair. The mechanism of action of dutasteride is not dissimilar from that of finasteride. It protects the hair follicles by reducing the levels of the biologically active metabolite DHT in the human body.
Who Orders Generic Avodart Online
Since Avodart is not yet an FDA approved drug for treating hair loss in men, not too many hair restoration doctors are willing to prescribe it to their patients off-label for treating this condition. In addition, being a relatively new drug Avodart (or generic dutasteride) is not yet available at all in many countries of the world. However, hair loss is a progressive condition and reversal is possible only in areas that started balding relatively recently. So time is your worst enemy when it comes to treating male pattern baldness. Hence, many hair loss patients buy cheap generic Avodart online not only because it is available at a great discount compared to the proprietary drug but also because it is their only option to get it. If you order Avodart from us you may rest assured that the whole process is safe, your order will be processed immediately and you will receive your generic Avodart pills in discreet packaging delivered directly to your doorstep.
Applications and Dosage of Generic Avodart (Dutasteride)
The recommended daily dose for treating both, enlarged prostate as well as male pattern baldness is 0.5mg of dutasteride, which is one capsule daily. Take this medication with or without food. Swallow the whole capsule. Use it regularly in order to get the most of it. If you miss a dose do not double it up in order to catch up. If dutasteride is used for treating hair loss, it may take 9-12 months before you notice any improvement in the thickness of your hair. Increasing the daily dose over 0.5mg will not improve or speed up hair regrowth but it can lead to increased side effects. Generic Avodart (dutasteride) may only be used by adult male patients.
Possible Side Effects of Generic Avodart (Dutasteride)
The following side effects have been reported by ca. 1% of patients taking Avodart (dutasteride). Many of these side effects can be managed and some may go away on their own over time. The list of recognized side effects includes the following: decreased sexual desire or ability, ejaculation disorders, weight gain and, less often, breast gland enlargement (gynecomastia) or breast tenderness. If such reactions occur, you are advised to interrupt the treatment and consult your doctor. These side effects are not too common but since dutasteride is a newer hair loss drug than finasteride, the exact percentage of patients affected has yet to be established. Some people may experience side effects other than those listed above. Check with your doctor if you notice any symptom that worries you while taking generic Avodart (dutasteride).
Safety Precautions While Using Generic Avodart (Dutasteride)
Blood donation: Patients taking this medication should not donate blood until at least 6 months have passed after their last dose. This is to prevent dutasteride being passed onto pregnant women during a blood transfusion.
Liver disease: Patients suffering from liver disease should discuss with their doctor how dutasteride may affect their health condition and, vice-versa, how their health condition may affect the dosing and effectiveness of this drug and whether any special monitoring would be required.
PSA test: Dutasteride can decrease PSA (prostate specific antigen) levels by up to 50%. Doctors often need to measure PSA levels in order to determine prostate cancer risks. If you are planning to have a PSA test, ensure your doctor knows that you are taking dutasteride. Although PSA levels can be measured if you are taking dutasteride, your doctor needs to know that so that he/she can adjust the results for accuracy.
Women and children: Dutasteride is intended for use by adult men only. Pregnant and breast-feeding women and children must avoid contact with dutasteride, as it is absorbed through the skin. If contact occurs, wash the exposed area immediately with soap and water. Women who may be pregnant must avoid touching capsules of dutasteride (even those that are not leaking) as dutasteride can cause abnormalities in the male baby's fetus.
What May Interact with Generic Avodart (Dutasteride)
Some drugs can interact with dutasteride such as:
- Macrolide antibiotics (e.g. clarithromycin, erythromycin)
- Protease inhibitors (e.g. ritonavir, indinavir, saquinavir)
- Azole antifungals (e.g. ketoconazole, fluconazole, itraconazole)
If you are taking any of these medications, speak with your doctor. Depending on your specific circumstances, your doctor may want you to either stop taking one of these medications or change them for another alternative or leave everything as it is.
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how possible drug interactions could be managed.
Storage of Avodart Capsules
Store at room temperature of ca. 77 degrees F (25 degrees C). Keep away from light, moisture and children. Brief storage between 59-86 degrees F (15-30 degrees C) is permitted.
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